Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/3153
Title: Ethanol extract of the Ieaves of Psidium Guajava Linn enhances sperm output in healthy wistar rats
Authors: Akinola, O.B
Oladosu, O.S
Dosumu, O.O
Keywords: Psidium guajava
antioxidants
male infertility
spermatozoa
Issue Date: 2007
Publisher: COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN, NIGERIA
Citation: Afr J Med Med Sci 2007, 36(2):137-140
Abstract: Reactive oxygen species (ROS), among other factors have been implicated in the aetiology of male infertility. Thus, the roles of antioxidants at improving sperm production and quality are being investigated. The present study was designed to assess the effect of the ethanol extract of fresh leaves of Psidium guajava Linn, on the sperm parameters of healthy male Wistar rats. A total of 18 rats, weighing between 108-124 g, were divided into 3 groups of 6 animals each. Animals in groups 1 and 2 were administered 250 mg/kg/d and 500 mg/kg/d of guava leaf extract (GLE) orally for 53 days respectively. Group 3 animals received normal saline. Sperm count increased from 56.2±0.3 (X106) in the control to 57.1 ±0.2 (X106) in group I animals, and from 56.2±0.3 (X106) in the control to 72.3±0.4 (X106) in group 2 animals. Similarly, dese-dependent increases in the percentages of motile spermatozoa were observed in GLE-treated animals compared to the control group. These findings suggest that the extracts of the leaves of Psidium guajava Linn. possess beneficial effects on sperm production and quality, and may thus improve the sperm parameters of infertile males with oligospermia and non-obstructive azoospermia.
Description: Article
URI: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/3153
ISSN: 1116-4077
Appears in Collections:African Journal of Medicine and Medical Sciences

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