Serum and seminal plasma hormonal profiles of infertile Nigerian male

Abstract

Male infertility constitutes a worldwide problem, especially in Nigeria where most men do not readily accept that they may contribute to the couple's infertility. In order to assess hormonal disturbances in the male infertility we compared male reproductive hormonal levels in human serum and seminal plasma and evaluated the hypothalamic-pituitary testicular-axis in infertile Nigerian males. The biophysical semen parameters were assessed by W.H.O. standard manual method . Scrum and seminal plasma mal e reproductive hormone s (Leutinizing hormones. Follicular stimulating hormone . Prolactin and Testosterone) were measured by Enzyme Immunoassay (EIA) technique of W.H.O. in sixty (60) infertile adult male Nigerian s (Oligospermic; n = 4 0 and azoopermic; n = 20) and forty controls of proven fertility (Normospermic subjects; n = 40). T h e results show that the serum concentrations of gonadotropins (LH and FSH) were significantly higher (/ 3 Male infertility constitutes a worldwide problem, especially in Nigeria where most men do not readily accept that they may contribute to the couple's infertility. In order to assess hormonal disturbances in the male infertility we compared male reproductive hormonal levels in human serum and seminal plasma and evaluated the hypothalamic-pituitary testicular-axis in infertile Nigerian males. The biophysical semen parameters were assessed by W.H.O. standard manual method . Scrum and seminal plasma mal e reproductive hormone s (Leutinizing hormones. Follicular stimulating hormone . Prolactin and Testosterone) were measured by Enzyme Immunoassay (EIA) technique of W.H.O. in sixty (60) infertile adult male Nigerian s (Oligospermic; n = 4 0 and azoopermic; n = 20) and forty controls of proven fertility (Normospermic subjects; n = 40). T h e results show that the serum concentrations of gonadotropins (LH and FSH) were significantly higher (/ 3