Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2792
Title: Case reporl: Extra pulmonary Tuberculosis in Sickle Cell Disease
Authors: Kehinde, A O
Olaniyi, J A
Fakunle, EE
Keywords: Immune status
Extra-pulmonary tuberculosis
Sickle cell disease
TB diagnostic facilities
Issue Date: Sep-2006
Publisher: COLLEGE OF MEDICINE
Citation: Afr. J. Med. med. Sci. (2006) 35, 381-384
Abstract: In apparently healthy individuals, tuberculosis (TB) affects mainly the lungs however, worsening immune status tend to predispose to an increased tendency for extra pulmonary tuberculosis (EPTB). We report the case of a 22 year old known sickle cell anaemia (HBS) female student with three-month history of bilateral hip pain, weight loss and swelling of the left hip with multiple discharging sinuses, paraplegia and recurrent fever. There was no preceding history of trauma. Full Blood Count (FBC) revealed leukocytosis with neutrophilia, monocytosis, thrombocytosis and Packed Cell Volume (PCV) of 23%. Erythrocyte sedimentation rate (ESR) was 120mm/Hr (Western Green) and retroviral screening was negative. Bacteriologic culture of the discharging sinuses grew Escherichia coli and Staphylococcus aureus. both sensitive to sparfloxacin. Smear microscopy for acid-fast-bacilli (AFB) was negative. Chest X-Ray was reported normal but X-Ray of the pelvis showed loss of L4/L5 disc space and appearances suggestive of avascular necrosis of the femoral heads. Clinical and haematological profile of the patient started to improve by the second month on therapeutic trial of anti TB regimen. She had nine-month course of therapy and later discharged to physiotherapy clinic. Management of EPTB requires a high index of clinical suspicion and well equipped laboratory to support the diagnosis. Therefore, this case report highlights the need to upgrade I B-diagnostic facilities in this environment
Description: Article
URI: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2792
ISSN: 1116-4077
Appears in Collections:African Journal of Medicine and Medical Sciences

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