Evaluation of the "One-minute" test for detecting Helicobacter (<Campylobacter) pylori infection

Abstract

The ••one-minute** urease test to detect Helicobacter (Campylobacter) pylori infection was evaluated using histology and culture as the *gokl standard**. The test was performed in a blinded manner and compared with the conventional Christensen's urease test. Helicobacter pylori was detected in 88 of 100 consecutive patients attending the gastrointestinal clinic for upper endoscopy. Although the "one-minute** urease test was more sensitive [86% (76/88)] than the conventional Christensen*s urease test (70% (62/88)1, this difference was not statistically significant (P - 0.22). Histology was the most sensitive [97% (85/88)1 whilst culture was 80% (70/88) sensitive. All tests exhibited specifications of 100%. The **one-minute** urease test is a simple, rapid and highly specific test to detect Helicobacter pylori which can be performed at endoscopy.