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Title: | ACIDITY AND INTESTINAL BACTERIA: AN IN-VITRO ASSESSMENT OF THE BACTERICIDAL ACTIVITY OF HYDROCHLORIC ACID ON INTESTINAL PATHOGENS |
Authors: | Rotimi, V. O Egwari, L Akande, B |
Keywords: | Hydrochloric acid Intestinal pathogens Gastric acidity Intestinal bacteria |
Issue Date: | 1990 |
Publisher: | BLACKWELL SCIENTIFIC PUBLICATIONS OXFORD |
Citation: | Afr. J. Med. med. Sci.1990:19. 275-280. |
Abstract: | The bactericidal activity of hydrochloric acid (MCI) on different intestinal bacteria was evaluated at various pH values and time intervals. The effect of HC1 was highest at pH 2 and pH 3 on strains of Campylobacter jejuni, Aeromonas hydrophila, Plesiomotias shigelloses, Yersinia enterocolitica, Salmonella spp. and Shigella spp., producing complete killing after 60 mill incubation. However, at higher pH values (pH4 and above), these organisms not only survived but also showed evidence of rapid multiplication. In contrast, clinical and standard strains of Escherichia coli and Staphylococcus aureus were resistant to all the pH values. The highest sensitivity to HCl was observed with strains of Shigella spp. and Salmonella spp. It is conceivable that patients with normal gastric acidity should not suffer from gastroenteritis caused by these intestinal pathogens. |
URI: | http://adhlui.com.ui.edu.ng/jspui/handle/123456789/1718 |
ISSN: | 1116-4077 |
Appears in Collections: | African Journal of Medicine and Medical Sciences |
Files in This Item:
File | Description | Size | Format | |
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Rotimi et al_Acidity_1990.pdf | Article | 6.98 MB | Adobe PDF | View/Open |
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