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DC Field | Value | Language |
---|---|---|
dc.contributor.author | ONUAGULUCHI, G. | - |
dc.contributor.author | IGBO, I. N. A. | - |
dc.date.accessioned | 2025-05-08T12:52:59Z | - |
dc.date.available | 2025-05-08T12:52:59Z | - |
dc.date.issued | 1990 | - |
dc.identifier.citation | Afr J Med Med Sci 1990, 19(4):307-312 | en_US |
dc.identifier.issn | 1116-4077 | - |
dc.identifier.uri | http://adhlui.com.ui.edu.ng/jspui/handle/123456789/4045 | - |
dc.description | Article | en_US |
dc.description.abstract | The effects of various i.v. doses of levamisole oil the ECG of the anaesthetized guinea-pigs were determined. At 6 mg/kg there were no changes in the heart rate, P -R and Q - T intervals and no cardiotoxic effects were observed. At 10 and 20 mg/kg these parameters were affected little but cardiotoxic effects, mainly ventricular extra systoles lasting from a few seconds to several minutes, were observed in five out of 10 animals that received either of the two doses. No animal died during the 1 h period of observation. It would appear that levamisole is much less toxic to the guinea-pig heart than to the heart of the rat. | en_US |
dc.description.sponsorship | COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN, NIGERIA | en_US |
dc.language.iso | en | en_US |
dc.publisher | COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN, NIGERIA | en_US |
dc.subject | Electrocardiographic changes | en_US |
dc.subject | levamisole hydrochloride | en_US |
dc.subject | guinea-pig | en_US |
dc.title | Electrocardiographic changes induced by levamisole hydrochloride in the guinea-pig | en_US |
dc.type | Article | en_US |
Appears in Collections: | African Journal of Medicine and Medical Sciences |
Files in This Item:
File | Description | Size | Format | |
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Onuaguluchi_Igbo_Electrocardiographic_1990.pdf | Article | 1.41 MB | Adobe PDF | View/Open |
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