COMUI (ADHL)
African Digital Health Library (ADHL) is a collection of theses, articles, books, videos, images, lectures, papers, data sets and all types of digital content originating from the College of Medicine, University of Ibadan, Nigeria.The ADHL in Nigeria is managed by E. Latunde Odeku Medical Library, College of Medicine, University of Ibadan. The ADHL is a collaborative initiative of medical librarians in Kenya, Mali, Nigeria, Zambia and Zimbabwe funded by the Office of Global AIDS/U.S. Department of State and the U.S. National Library of Medicine / National Institutes of Health.
Please use this identifier to cite or link to this item:
http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2925Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Iranloye, B.O | - |
| dc.contributor.author | Owoyele, V.B | - |
| dc.contributor.author | Kelani, O.R | - |
| dc.contributor.author | Olaleye, S.B | - |
| dc.date.accessioned | 2024-09-19T09:30:01Z | - |
| dc.date.available | 2024-09-19T09:30:01Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier.citation | Afr. J. Med. med. Sci. (2011) 40, 47-50 | en_US |
| dc.identifier.issn | 1116-4077 | - |
| dc.identifier.uri | http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2925 | - |
| dc.description | Article | en_US |
| dc.description.abstract | Various doses of the aqueous extract of Phyllanthus amarus (AEPA) were investigated for analgesic and anti-inflammatory activities using both thermal and chemical models of pain assessment in rats. The extract caused a significant (P< 0.05) dose related increase inhibition of the carrageenan-induced paw oedema in the rats. The inhibition produced by 200mg/kg AEPA (70.20%) was significantly higher than that of the reference drug (Acetylsalicylic acid). The extract produced a marked analgesic activity by inhibiting both early and late phases of pain stimulus in Formalininduced paw licking rats and also a significant and dose related increase in inhibiting the mean tail immersion duration (MITD) at varying water bath temperature (50°C, 55°C and COX). This study thus established the anti-inflammatory and analgesic activities of Phyllanthus amarus. | en_US |
| dc.description.sponsorship | COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN, NIGERIA | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN, NIGERIA | en_US |
| dc.subject | Phyllanthus amarus; | en_US |
| dc.subject | Pnalgesic | en_US |
| dc.subject | Pain | en_US |
| dc.subject | Anti-inflammatory | en_US |
| dc.title | Analgesic activity of aqueous leaf extract of Phyllanthus Amarus | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | African Journal of Medicine and Medical Sciences | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Iranloye et al_ Analgesic_2011.pdf | Article | 6.6 MB | Adobe PDF | View/Open |
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