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dc.contributor.authorOYEYINKA, G. O.-
dc.date.accessioned2024-07-01T10:57:18Z-
dc.date.available2024-07-01T10:57:18Z-
dc.date.issued1988-12-
dc.identifier.citationAfr. J. Med. med. Sci. (1988) 17. 201-207.en_US
dc.identifier.issn1116-4077-
dc.identifier.urihttp://adhlui.com.ui.edu.ng/jspui/handle/123456789/2026-
dc.descriptionArticleen_US
dc.description.abstractThe clinical and pathological features of malaria have been well recognized for a long time. Macroglobulinaemia accompanies malarial infections and these patients have increased susceptibility to secondary infection. They may also have splenic enlargement. However, how these changes are brought about is still not fully explained. For over a decade many researchers have looked into the possibility of a parasite-derived mitogen being partly responsible for some of these features. This paper appraises, in the light of evidence so far advanced, the role of mitogenic factors in the pathogenesis of hypergammaglobulinemia, immunosuppression and splenomegaly associated with malarial infection. The nature of the stimulatory material in parasite extracts is also discussed.en_US
dc.description.sponsorshipCOLLEGE OF MEDICINEen_US
dc.language.isoenen_US
dc.publisherBLACKWELL SCIENTIFIC PUBLICATIONSen_US
dc.subjectclinicalen_US
dc.subjectpathologicalen_US
dc.subjectmalariaen_US
dc.subjectinfectionsen_US
dc.subjectdecadeen_US
dc.subjectresearchersen_US
dc.titleThe role of mitogenic factors in the pathogenesis of certain features of malarial infectionen_US
dc.typeArticleen_US
Appears in Collections:African Journal of Medicine and Medical Sciences

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