Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/1874
Title: Endocrine function and haemoglobinopathies: biochemical assessment of thyroid function in children with sickle-cell disease
Authors: LUKANMBI, F. A.
ADEYOKUNNU, A. A.
OSIFO, B. O. A.
BOLODEOKU, J. O.
DADA, O. A.
Keywords: Thyroid
Genotype
Children
Sickle-cell disease
Haemoglobin
Issue Date: Mar-1986
Publisher: COLLEGE OF MEDICINE
Citation: Afr. J. Med. med. Sci. (1986) 15(1/2): 25-28.
Abstract: Thyroid function was assessed in ninety children with homozygous sickle-cell disease (haemoglobin genotype SS) in forty-five children with heterozygous sickle-cell trait (AS) and in 162 control children with haemoglobin genotype AA. Serum levels of thyroxine, the in vitro triidothyronine resin uptake, and the calculated index of "free thyroxine" were not significantly different in the three groups. The distribution of individual thyrotropin (TSH) values showed that only 11% of the HbSS subjects had values below the 95% confidence limits for the HbAA controls. However, the mean level of TSH was significantly lower in the HbSS than the other two groups of children
Description: Article
URI: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/1874
ISSN: 1116-4077
Appears in Collections:African Journal of Medicine and Medical Sciences

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