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dc.contributor.authorOGUNBONA, F. A-
dc.contributor.authorADEDOYIN, P. A-
dc.contributor.authorOLANIYI, A. A-
dc.date.accessioned2023-01-24T13:13:10Z-
dc.date.available2023-01-24T13:13:10Z-
dc.date.issued1985-
dc.identifier.citationAfr. J. Med. med. Sci. (1985) 14. 21-25.en_US
dc.identifier.issn1116-4077-
dc.identifier.urihttp://adhlui.com.ui.edu.ng/jspui/handle/123456789/1844-
dc.descriptionArticleen_US
dc.description.abstractThe chemical and biological equivalence of two brands of diazepam tablets marketed in Nigeria were compared to that of Valium (Roche) tablets. The tablets used were Relanium (Polfa) and Tropium (Biode). Bioequivalence studies of the brands were carried out on nine healthy volunteers by monitoring the cumulative diazepam excreted as oxazepam (both free and conjugated) in urine over 48 h. The bioequivalence of Relanium was found not to be significantly different from that of Valium while that of Tropium was significantly different from that of Valium (P < 0.05). The results of the investigation showed that the drug products were all chemical equivalents but not biological equivalents.en_US
dc.description.sponsorshipCollege of Medicine, University of Ibadanen_US
dc.language.isoenen_US
dc.publisherBLACKWELL SCIENTIFIC PUBLICATIONSen_US
dc.subjectDiazepam tabletsen_US
dc.subjectValiumen_US
dc.subjectBioequivalence studiesen_US
dc.subjectOxazepamen_US
dc.titleComparative Bioavailability Studies on Brands of Diazepam Tabletsen_US
dc.typeArticleen_US
Appears in Collections:African Journal of Medicine and Medical Sciences

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