COMUI (ADHL)
African Digital Health Library (ADHL) is a collection of theses, articles, books, videos, images, lectures, papers, data sets and all types of digital content originating from the College of Medicine, University of Ibadan, Nigeria & managed by E. Latunde Odeku Medical Library.
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http://adhlui.com.ui.edu.ng/jspui/handle/123456789/4045| Title: | Electrocardiographic changes induced by levamisole hydrochloride in the guinea-pig |
| Authors: | ONUAGULUCHI, G. IGBO, I. N. A. |
| Keywords: | Electrocardiographic changes levamisole hydrochloride guinea-pig |
| Issue Date: | 1990 |
| Publisher: | COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN, NIGERIA |
| Citation: | Afr J Med Med Sci 1990, 19(4):307-312 |
| Abstract: | The effects of various i.v. doses of levamisole oil the ECG of the anaesthetized guinea-pigs were determined. At 6 mg/kg there were no changes in the heart rate, P -R and Q - T intervals and no cardiotoxic effects were observed. At 10 and 20 mg/kg these parameters were affected little but cardiotoxic effects, mainly ventricular extra systoles lasting from a few seconds to several minutes, were observed in five out of 10 animals that received either of the two doses. No animal died during the 1 h period of observation. It would appear that levamisole is much less toxic to the guinea-pig heart than to the heart of the rat. |
| Description: | Article |
| URI: | http://adhlui.com.ui.edu.ng/jspui/handle/123456789/4045 |
| ISSN: | 1116-4077 |
| Appears in Collections: | African Journal of Medicine and Medical Sciences |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Onuaguluchi_Igbo_Electrocardiographic_1990.pdf | Article | 1.41 MB | Adobe PDF | View/Open |
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