Analgesic activity of aqueous leaf extract of Phyllanthus Amarus

Iranloye, B.O; Owoyele, V.B; Kelani, O.R; Olaleye, S.B

Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2925

Full metadata record

DC Field	Value	Language
dc.contributor.author	Iranloye, B.O	-
dc.contributor.author	Owoyele, V.B	-
dc.contributor.author	Kelani, O.R	-
dc.contributor.author	Olaleye, S.B	-
dc.date.accessioned	2024-09-19T09:30:01Z	-
dc.date.available	2024-09-19T09:30:01Z	-
dc.date.issued	2011	-
dc.identifier.citation	Afr. J. Med. med. Sci. (2011) 40, 47-50	en_US
dc.identifier.issn	1116-4077	-
dc.identifier.uri	http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2925	-
dc.description	Article	en_US
dc.description.abstract	Various doses of the aqueous extract of Phyllanthus amarus (AEPA) were investigated for analgesic and anti-inflammatory activities using both thermal and chemical models of pain assessment in rats. The extract caused a significant (P< 0.05) dose related increase inhibition of the carrageenan-induced paw oedema in the rats. The inhibition produced by 200mg/kg AEPA (70.20%) was significantly higher than that of the reference drug (Acetylsalicylic acid). The extract produced a marked analgesic activity by inhibiting both early and late phases of pain stimulus in Formalininduced paw licking rats and also a significant and dose related increase in inhibiting the mean tail immersion duration (MITD) at varying water bath temperature (50°C, 55°C and COX). This study thus established the anti-inflammatory and analgesic activities of Phyllanthus amarus.	en_US
dc.description.sponsorship	COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN, NIGERIA	en_US
dc.language.iso	en	en_US
dc.publisher	COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN, NIGERIA	en_US
dc.subject	Phyllanthus amarus;	en_US
dc.subject	Pnalgesic	en_US
dc.subject	Pain	en_US
dc.subject	Anti-inflammatory	en_US
dc.title	Analgesic activity of aqueous leaf extract of Phyllanthus Amarus	en_US
dc.type	Article	en_US
Appears in Collections:	African Journal of Medicine and Medical Sciences

Files in This Item:

File	Description	Size	Format
Iranloye et al_ Analgesic_2011.pdf	Article	6.6 MB	Adobe PDF	View/Open

Show simple item record

COMUI (ADHL)

African Digital Health Library (ADHL) is a collection of theses, articles, books, videos, images, lectures, papers, data sets and all types of digital content originating from the College of Medicine, University of Ibadan, Nigeria & managed by E. Latunde Odeku Medical Library.