Plasma nicotinic acid level in chloroquine treated rats

Kukoyi, B I; Alemnji, G A

Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2114

Full metadata record

DC Field	Value	Language
dc.contributor.author	Kukoyi, B I	-
dc.contributor.author	Alemnji, G A	-
dc.date.accessioned	2024-07-12T11:43:12Z	-
dc.date.available	2024-07-12T11:43:12Z	-
dc.date.issued	2000-03	-
dc.identifier.citation	Afr. J. Med. med Sci. (2000) 29, 45 - 46	en_US
dc.identifier.issn	1116-4077	-
dc.identifier.uri	http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2114	-
dc.description	ARTICLE	en_US
dc.description.abstract	The effect of chloroquine phosphate on plasma nicotinic acid levels in adult male albino rats was investigated. Pyrogen free chloroquine phosphate in physiological saline was administered subcutaneously to rats in a dose of 15mg/kg body weight daily for eleven succeeding days in the treatment group. A control group was given equal volume of physiological saline daily for eleven succeeding days. Nicotinic acid concentration in the plasma was determined [ 1] Plasma nicotinic acid level was found to be significantly reduced ( P <0.01) throughout the duration of treatment. No change was observed in the control group. The significant reduction of plasma nicotinic acid level observed in this study may not be unrelated to competitive inhibition of the enzyme tryptophan dioxygenase by chloroquine phosphate	en_US
dc.description.sponsorship	COLLEGE OF MEDICINE,UNIVERSITY OF IBADAN	en_US
dc.language.iso	en	en_US
dc.publisher	COLLEGE OF MEDICINE.UNIVERSITY OF IBADAN	en_US
dc.subject	Nicotinic acid	en_US
dc.subject	chloroquine phosphate	en_US
dc.subject	physiological saline	en_US
dc.subject	Pyrogen	en_US
dc.title	Plasma nicotinic acid level in chloroquine treated rats	en_US
dc.type	Article	en_US
Appears in Collections:	African Journal of Medicine and Medical Sciences

Files in This Item:

File	Description	Size	Format
kukoyi_Alemnji_Plasma_2000.pdf	ARTICLE	6.61 MB	Adobe PDF	View/Open

Show simple item record

COMUI (ADHL)

African Digital Health Library (ADHL) is a collection of theses, articles, books, videos, images, lectures, papers, data sets and all types of digital content originating from the College of Medicine, University of Ibadan, Nigeria & managed by E. Latunde Odeku Medical Library.