Endocrine function and haemoglobinopathies: biochemical assessment of thyroid function in children with sickle-cell disease

LUKANMBI, F. A.; ADEYOKUNNU, A. A.; OSIFO, B. O. A.; BOLODEOKU, J. O.; DADA, O. A.

Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/1874

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DC Field	Value	Language
dc.contributor.author	LUKANMBI, F. A.	-
dc.contributor.author	ADEYOKUNNU, A. A.	-
dc.contributor.author	OSIFO, B. O. A.	-
dc.contributor.author	BOLODEOKU, J. O.	-
dc.contributor.author	DADA, O. A.	-
dc.date.accessioned	2023-02-03T11:03:19Z	-
dc.date.available	2023-02-03T11:03:19Z	-
dc.date.issued	1986-03	-
dc.identifier.citation	Afr. J. Med. med. Sci. (1986) 15(1/2): 25-28.	en_US
dc.identifier.issn	1116-4077	-
dc.identifier.uri	http://adhlui.com.ui.edu.ng/jspui/handle/123456789/1874	-
dc.description	Article	en_US
dc.description.abstract	Thyroid function was assessed in ninety children with homozygous sickle-cell disease (haemoglobin genotype SS) in forty-five children with heterozygous sickle-cell trait (AS) and in 162 control children with haemoglobin genotype AA. Serum levels of thyroxine, the in vitro triidothyronine resin uptake, and the calculated index of "free thyroxine" were not significantly different in the three groups. The distribution of individual thyrotropin (TSH) values showed that only 11% of the HbSS subjects had values below the 95% confidence limits for the HbAA controls. However, the mean level of TSH was significantly lower in the HbSS than the other two groups of children	en_US
dc.description.sponsorship	COLLEGE OF MEDICINE	en_US
dc.language.iso	en	en_US
dc.publisher	COLLEGE OF MEDICINE	en_US
dc.subject	Thyroid	en_US
dc.subject	Genotype	en_US
dc.subject	Children	en_US
dc.subject	Sickle-cell disease	en_US
dc.subject	Haemoglobin	en_US
dc.title	Endocrine function and haemoglobinopathies: biochemical assessment of thyroid function in children with sickle-cell disease	en_US
dc.type	Article	en_US
Appears in Collections:	African Journal of Medicine and Medical Sciences

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